Biology decoded,
disease undone

Modulating transcription factor activity to restore health

Drug discovery is coming from the wrong direction: targeting the downstream consequences of disease rather than the underlying biological causes.

It’s time to flip the script. 

By focusing on understanding and manipulating the master controllers of biology, we’re searching for drugs with the potential not just to delay disease progression, but to halt or even reverse it. 

Flipping the script on drug discovery

Scripta is exploiting the unique information-rich properties of transcription factors to turn drug discovery on its head.

Built on best-in-class AI/ML models, our unbiased approach can be applied to any disease, revealing novel therapeutics with the potential to deliver transformative outcomes.

We start with genome-wide mapping of the transcription factors defining and driving disease. Next, we identify and predict molecules and targets that modulate them.

Finally, we close the loop by validating the results in our pre-mapped, patient-derived models.

Our first focus is finding therapies that truly change the course of neurodegenerative diseases such as Alzheimer’s, Parkinson’s and ALS.

A scientist wearing a white lab coat and safety glasses observes a computer screen displaying fluorescent microscopy images of cells. The monitor shows software with a central image of green and blue-stained cells, likely indicating cellular structures such as nuclei and cytoskeleton. The setting appears to be a modern laboratory with bright lighting and scientific equipment.
A scientist wearing a white lab coat and safety glasses observes a computer screen displaying fluorescent microscopy images of cells. The monitor shows software with a central image of green and blue-stained cells, likely indicating cellular structures such as nuclei and cytoskeleton. The setting appears to be a modern laboratory with bright lighting and scientific equipment.
A scientist wearing a white lab coat and safety glasses observes a computer screen displaying fluorescent microscopy images of cells. The monitor shows software with a central image of green and blue-stained cells, likely indicating cellular structures such as nuclei and cytoskeleton. The setting appears to be a modern laboratory with bright lighting and scientific equipment.

Scientific leadership

We’re a dedicated team combining pharma, biotech and disease biology expertise with the computational power to push the boundaries of biology and deliver on our goal: disease modifying therapeutics that will make a real difference to patients.

CEO and Founder

Peter Hamley

Peter Hamley, CEO of Scripta

CEO and Founder

Peter Hamley

Peter Hamley, CEO of Scripta

CEO and Founder

Peter Hamley

Peter Hamley, CEO of Scripta

VP of Machine Learning

Jerry Huang

VP of Machine Learning

Jerry Huang

VP of Machine Learning

Jerry Huang

VP of Bioinformatics

Andy Walker

Andy Walker, Head of Bioinformatics at Scripta

VP of Bioinformatics

Andy Walker

Andy Walker, Head of Bioinformatics at Scripta

VP of Bioinformatics

Andy Walker

Andy Walker, Head of Bioinformatics at Scripta

VP of Biology

John Blackwood

John Blackwood
John Blackwood

VP of Biology

John Blackwood

John Blackwood
John Blackwood

VP of Biology

John Blackwood

John Blackwood
John Blackwood

Academic co-founder

Prof. Noel Buckley

Prof. Noel Buckley
Prof. Noel Buckley

Academic co-founder

Prof. Noel Buckley

Prof. Noel Buckley
Prof. Noel Buckley

Academic co-founder

Prof. Noel Buckley

Prof. Noel Buckley
Prof. Noel Buckley

Our board

We're proud to be backed by a phenomenal consortium of VCs, all of whom are represented on our Board with either Board members or observers.

Non-Executive Director

Raymond Barlow

Raymond Barlow
Raymond Barlow

Non-Executive Director

Raymond Barlow

Raymond Barlow
Raymond Barlow

Non-Executive Director

Raymond Barlow

Raymond Barlow
Raymond Barlow

Oxford Science Enterprises

Claire Brown

Claire Brown
Claire Brown

Oxford Science Enterprises

Claire Brown

Claire Brown
Claire Brown

Oxford Science Enterprises

Claire Brown

Claire Brown
Claire Brown

Apollo Health Ventures

Marianne Mertens

Marianne Mertens
Marianne Mertens

Apollo Health Ventures

Marianne Mertens

Marianne Mertens
Marianne Mertens

Apollo Health Ventures

Marianne Mertens

Marianne Mertens
Marianne Mertens

Investors:

Join the team

We’re on a mission to deliver transformative therapeutics that will change lives. If you have the ambition to match ours, we want to hear from you.

Join the team

We’re on a mission to deliver transformative therapeutics that will change lives. If you have the ambition to match ours, we want to hear from you.

Join the team

We’re on a mission to deliver transformative therapeutics that will change lives. If you have the ambition to match ours, we want to hear from you.

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